Recombinant Human Cystatin C
Cystatin C (Cys-C) is a cysteine protease inhibitor and a common indicator of kidney function. It is also reported to play a role in cardiovascular and neurological diseases. The recombinant Cystatin C is expressed as a monomer with an apparent molecular mass of 12 to 13 kDa. SAR408
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Source: |
HEK293 cells
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Purity:
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Above ≥ 95% by SDS-PAGE% as determined by SDS-PAGE Analysis.
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Cross Reactivity: |
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Biological Activity
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The specific activity is determined by measuring the inhibition of papin’s protease activity and measured to be 0.3–1.5 µM IC50. The colorimetric assay was done using L-BAPA as substrate in presence of 0.55μM papain and 0.44μM L-BAPA.
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AA Sequence
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MAGPLRAPL LLLAILAVA LAVSPAAGS SPGKPPRLV GGPMDASVE EEGVRRALD FAVGEYNKA SNDMYHSRA LQVVRARKQ IVAGVNYFL DVELGRTTC TKTQPNLDN CPFHDQPHL KRKAFCSFQ IYAVPWQGT MTLSKSTCQ DA
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