by SEM (n = levels in 0.01, by 16 weeks immediately after nephrectomy. Values are presented because the p 0.05, SEMANOVA and Tukey HSD (versus control group). (versus CS and control group). # p 0.05, by (n = 6). p 0.01, by ANOVA and Tukey HSD ANOVA and Tukey HSD (versus control group).two.7.two. Peroxynitrate (ONOO- ) LevelMar. Drugs 2021, 19, x FOR PEER REVIEW9 of 18 Figure eight shows the ONOO 2.7.2. Peroxynitrate (ONOO-) Level – level in the kidney at 16 weeks right after nephrectomy (Figure 8). The ONOO- level was significantly at 16 weeks right after nephrectomy groups. Figure 8 shows the ONOO- level inside the kidney decreased in the ARA + DHA (Figure8). The ONOO- level was substantially decreased inside the ARA+DHA groups.Figure 8. ONOO- levels in kidney at 16 weeks right after nephrectomy. Values are presented because the mean ONOO- kidney 16 weeks soon after nephrectomy. Values are presented as the imply EM (n = six). pp0.01, by ANOVA and Tukey HSD (versus ARA group). # p 0.05, by ANOVA 0.01, by ANOVA and Tukey ANOVA SEM (n = 6). group). # p 0.05, and Tukey HSD (versus handle group). Tukey HSD (versus control group).2.7.3. Lipid Peroxides (LPO) Level in the Kidney and Plasma two.7.3. Lipid Peroxides (LPO) Level within the Kidney and Plasma Figure 9 shows LPO levels within the kidney and plasma at 4 and 16 weeks immediately after nephrecFigure 9 shows LPO levels in the kidney and plasma at 4 and 16 weeks right after nephrectomy (Figure 9A ). LPO levels within the kidney showed no considerable differences among tomy (Figure 9A ). LPO levels within the kidney showed no considerable differences among the 5 groups. LPO level in plasma was drastically improved 5-HT3 Receptor Antagonist web following 4 weeks, but it was the five groups. LPO level in plasma was considerably enhanced after 4 weeks, however it was attenuated in the ARA + DHA group. Interestingly, there were no substantial differences attenuated in the ARA+DHA group. Interestingly, there were no considerable differences 5-HT2 Receptor Modulator manufacturer amongst the 5 groups following 16 weeks of nephrectomy. among the 5 groups following 16 weeks of nephrectomy.2.7.3. Lipid Peroxides (LPO) Level within the Kidney and Plasma Figure 9 shows LPO levels in the kidney and plasma at 4 and 16 weeks after nephrectomy (Figure 9A ). LPO levels in the kidney showed no considerable variations amongst the five groups. LPO level in plasma was drastically elevated just after 4 weeks, but it9was of 17 attenuated within the ARA+DHA group. Interestingly, there were no significant differences among the five groups just after 16 weeks of nephrectomy.Mar. Drugs 2021, 19,Figure LPO (A) within the kidney at weeks; (B) in Figure 9. LPO levels in kidney and plasma at four and 16 weeks just after nephrectomy. (A) inside the kidney at 16 weeks; (B) in plasma at 4 weeks, and (C) plasma at 16 weeks. Values are presented as the mean SEM (n = six). p 0.05, by ANOVA SEM (n = six). p 0.05, by ANOVA are presented because the mean and Tukey HSD (versus CS group). # p 0.05, by ANOVA and Tukey HSD (versus control group). Tukey HSD (versus manage group). and Tukey 0.05, by ANOVA2.eight. Cytokine Levels within the Kidney Figure ten shows cytokine levels in the kidney at 16 weeks following nephrectomy (Figure 10A ). IL-6 level was not significantly diverse amongst the 5 groups at 16 weeks soon after nephrectomy. TNF- and TGF-1 levels had been considerably increased following nephrectomy, but TGF-1 levels have been considerably decreased in the ARA, DHA, and ARA + DHA groups. 2.9. Correlations among Renal Functions and LPO Levels in Plasma Figure 11 shows correlations among Ccr and LPO levels in plasma (Figure 11A,B), and urinary