Name : TNF-α, Human
Product Concentration :
Background :
Tumor Necrosis Factor-alpha (TNF-a) is a homotrimer with a subunit molecular mass of 17.3 kDa. Tumor Necrosis Factor-alpha(TNF-a) plays a major role in growth regulation, differentiation, inflammation, viral replication, tumorigenesis, and autoimmune diseases; and in viral, bacterial, fungal, and parasitic infections. Besides inducing hemorrhagic necrosis of tumors, TNF has been found to be involved in tumorigenesis, tumor metastasis, viral replication, septic shock, fever, inflammation, and autoimmune diseases including Crohn’s disease, and rheumatoid arthritis as well as graft-versus-host disease.
Biological Activity :
TNF-alpha, Human (Cat. No. Z01001) stimulates cytotoxicity of L-929 mouse fibrosarcoma cells. The ED50 for this effect is typically 11-50 pg/mL. 2 μg of TNF-α, Human (Cat. No. Z01001) was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie Blue staining. TNF-α, Human Tumor Necrosis Factor-alpha (TNF-a) is a homotrimer with a subunit molecular mass of 17.3 kDa. Tumor Necrosis Factor-alpha(TNF-a) plays a major role in growth regulation, differentiation, inflammation, viral replication, tumorigenesis, and autoimmune diseases; and in viral, bacterial, fungal, and parasitic infections. Besides inducing hemorrhagic necrosis of tumors, TNF has been found to be involved in tumorigenesis, tumor metastasis, viral replication, septic shock, fever, inflammation, and autoimmune diseases including Crohn’s disease, and rheumatoid arthritis as well as graft-versus-host disease. .hide { display: none!important; } .product_table_cart_div{ width: 100%; } .product_table_cart_div .unit{ display: block; font-weight: bold; min-width: 120px; text-align: left; width: 100px; } .form-control{ width: 45px; height: 30px; line-height: 30px; display: inline; padding: 0px 0px 0px 5px; } .product_table_cart_div .size-box{ padding: 4px 5px; border: 1px solid #cccccc; text-align: center; margin-right: 10px; } .product_table_cart_div span{ color: black !important; } .product_table_cart_div .price{ font-weight: 600; font-style: normal; color: #1D73DD; font-size: 30px; text-align: left; color: #F41D27 !important; } .product_table_cart_div .price-td{ padding-bottom:50px !important; } .btn-add-to-cart .button-face{ height: 40px; font-size: 16px; } .size-list div{ display: inline-block; } .ask-us{ color: #1D73DD; margin: 0 10px; } .btn-add-to-cart{ width: 180px; }
expression system :
E. coli
Tag :
TNF-α (Val77-Leu233)Accession # P01375
Protein Accession No. :
P01375
Synonyms :
TNF-alpha; Tumor necrosis factor ligand superfamily member 2; TNF-a; Cachectin; DIF; TNFA; TNFSF2
Molecular Weight :
~17.3 kDa, on SDS-PAGE under reducing conditions.
Purity :
> 98% as analyzed by SDS-PAGE> 98% as analyzed by HPLC
Product Concentration :
Lyophilized after extensive dialysis against PBS.
Storage and Stability :
Upon receiving, this product remains stable for up to 6 months at lower than -70°C. Upon reconstitution, the product should be stable for up to 1 week at 4°C or up to 3 months at -20°C. For long term storage it is recommended that a carrier protein (example 0.1% BSA) be added. Avoid repeated freeze-thaw cycles.
Related category websites: https://www.medchemexpress.com/recombinant-proteins.html
Popular product recommendations:
Thrombomodulin Protein
Aminopeptidase N/APN Protein
Popular categories:
gp130/CD130
VEGF-A