Product Name :
TAK-041
Description:
TAK-041 is a potent and selective GPR139 agonist with an EC50 of 22 nM. TAK-041 has the potential for the research of negative symptoms associated with schizophrenia.
CAS:
1929519-13-0
Molecular Weight:
392.33
Formula:
C18H15F3N4O3
Chemical Name:
2-(4-oxo-3, 4-dihydro-1, 2, 3-benzotriazin-3-yl)-N-[(1S)-1-[4-(trifluoromethoxy)phenyl]ethyl]acetamide
Smiles :
C[C@H](NC(=O)CN1N=NC2=CC=CC=C2C1=O)C1C=CC(=CC=1)OC(F)(F)F
InChiKey:
JZGLECLGVQRPPI-NSHDSACASA-N
InChi :
InChI=1S/C18H15F3N4O3/c1-11(12-6-8-13(9-7-12)28-18(19,20)21)22-16(26)10-25-17(27)14-4-2-3-5-15(14)23-24-25/h2-9,11H,10H2,1H3,(H,22,26)/t11-/m0/s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.KH-3 site
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.(S)-(-)-Levamisole Protocol
Additional information:
TAK-041 is a potent and selective GPR139 agonist with an EC50 of 22 nM.PMID:33309404 TAK-041 has the potential for the research of negative symptoms associated with schizophrenia.|Product information|CAS Number: 1929519-13-0|Molecular Weight: 392.33|Formula: C18H15F3N4O3|Chemical Name: 2-(4-oxo-3, 4-dihydro-1, 2, 3-benzotriazin-3-yl)-N-[(1S)-1-[4-(trifluoromethoxy)phenyl]ethyl]acetamide|Smiles: C[C@H](NC(=O)CN1N=NC2=CC=CC=C2C1=O)C1C=CC(=CC=1)OC(F)(F)F|InChiKey: JZGLECLGVQRPPI-NSHDSACASA-N|InChi: InChI=1S/C18H15F3N4O3/c1-11(12-6-8-13(9-7-12)28-18(19,20)21)22-16(26)10-25-17(27)14-4-2-3-5-15(14)23-24-25/h2-9,11H,10H2,1H3,(H,22,26)/t11-/m0/s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : 100 mg/mL (254.89 mM; Need ultrasonic).|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vivo:|TAK-041 (0.03-3 mg/kg; P.o.) improves social behavior in BALB/c mice.|Products are for research use only. Not for human use.|