IL-1 beta Protein

Description:
|Introduction Interleukin-1b is produced by activated macrophages, IL-1B stimulates thymocyte proliferation by inducing il-2 release, b-cell maturation and proliferation, and fibroblast growth factor activity. IL1B proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells. |Reco|E. coli-derived. A non-glycosylated, Polypeptide chain containing 153 amino acids and having a molecular mass of 17000 Dalton. N-terminal sequence analysis: Ala-Pro-Val-Arg-Ser. The specific activity as determined in the test of augmentation of lymphocyte prolifiration assay using mouse thymus was found to be 200,000,000 IU/mg. Purity: > 98% by SDS-|Lyophilized from a concentrated (1 ug/ml) sterile solution containing 50 mM Phosphate buffer pH=7.1 and 150 mM NaCl. Reconstitution: It is recommended to reconstitute the lyophilized Interleukin-1b in sterile 18 M?-cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions. Shipping: The product is shipped at a|Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70°C as supplied. 1 month, 2 to 8°C under sterile conditions after reconstitution. 3 months, -20 to -70°C under sterile conditions after reconstitution.