IL-15 Protein

Description:
|Introduction Human Interleukin 15 (IL-15) is a cytokine that regulates T cell and natural killer cell activation and proliferation. IL-15 binds to the alpha subunit of the IL15 receptor (IL-15RA) with high affinity. IL-15 also binds to the beta and gamma chains of the IL-2 receptor, but not the alpha subunit of the IL2 receptor. IL-15 is structurally and functionally related to IL-2. Both cytokines share some subunits of receptors, allowing them to compete for and negatively regulate each other’s activity. The nu|E. coli-derived. A single, non-glycosylated polypeptide chain containing 114 amino acids and having a molecular mass of 12774 Dalton. The ED50 as determined by the dose-dependant stimulation of the proliferation of mouse CTLL-2 was found to be Purity: > 98% by SDS-|Lyophilized from a concentrated (1 ug/ml) solution with 5 mM Tris pH 8.0. Reconstitution: It is recommended to reconstitute the lyophilized Interleukin-15 in sterile 18 M?-cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions. Shipping: The product is shipped at a|Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70°C as supplied. 1 month, 2 to 8°C under sterile conditions after reconstitution. 3 months, -20 to -70°C under sterile conditions after reconstitution. |Other IL-15 Proteins: Reco|IL-15 Monoclonal Antibody