IL-19 Protein

Description:
|Introduction IL19 is a cytokine that belongs to the IL10 cytokine subfamily. IL-19 is found to be preferentially expressed in monocytes. It can bind the IL20 receptor complex and lead to the activation of the signal transducer and activator of transcription 3 (STAT3). A similar cytokine in mouse is reported to up-regulate the expression of IL6 and TNF-alpha and induce apoptosis, which suggests a role of this cytokine in inflammatory responses. Alternatively spliced transcript variants encoding the distinct isoforms have been described. |Reco|E. coli-derived. A single, non-glycosylated polypeptide chain containing 155 amino acids and having a molecular mass of 17913 Dalton. N-terminal sequence analysis: Met-Leu-Arg-Arg-Cys. The activity is determined by it’s ability to activate STAT following receptor-ligand interaction. Purity > 99%, by SDS-|Lyophilized from a concentrated (1 ug/ml) solution in water containing 10 mM sodium citrate pH-5. Reconstitution: It is recommended to reconstitute the lyophilized Interleukin-19 in sterile 18 M?-cm H2O at a concentration of 0.5 ug/ml or less. Shipping: The product is shipped at a|Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70°C as supplied. 1 month, 2 to 8°C under sterile conditions after reconstitution. 3 months, -20 to -70°C under sterile conditions after reconstitution. |Other IL-19 Protein: Recombinant Mouse IL-19