IL-2 Protein

Description:
|Introduction IL2 is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis-like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli. |Reco|E. coli-derived. A single, non-glycosylated mutein (variant form) of human IL-2 polypeptide chain containing 134 amino acids and having a molecular mass of 15517 Dalton. N-terminal sequence analysis: Met-Ala-Pro-Thr-Ser. The ED50 as determined by the dose-dependant stimulation of murine CTLL-2 cells is Purity: > 98% by SDS-|Lyophilized after extensive dialysis against 0.17 mg sodium monobasic & 0.89 mg dibasic sodium phosphate buffer to a pH=7.5. Reconstitution: It is recommended to reconstitute the lyophilized Interleukin 2 in sterile 20 mM AcOH not less than 100 ug/ml, which can then be further diluted to other aqueous solutions. Shipping: The product is shipped at a|Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70°C as supplied. 1 month, 2 to 8°C under sterile conditions after reconstitution. 3 months, -20 to -70°C under sterile conditions after reconstitution. |Other IL-2 Proteins: Reco|IL-2 Polyclonal Antibody IL-2 Polyclonal Antibody IL-2 Monoclonal Antibody IL-2 Monoclonal Antibody IL-2 Monoclonal Antibody