IL-2 Protein

Description:
|Introduction IL2 is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis-like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli. |Reco|E. coli-derived. A single, non-glycosylated polypeptide chain containing 148 amino acids and having a molecular mass of 17231 Dalton. The ED50 as determined by the dose-dependant stimulation of murine CTLL-2 cells is 0.18 ug/ml corresponding to a Specific Activity of 55 MIU/mg. Purity: > 98% by SDS-|Lyophilized extensive dialysis against 10 mM sodium citrate buffer to a pH=4. Reconstitution: It is recommended to reconstitute the lyophilized Mouse IL-2 in sterile 18 M?-cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions. Shipping: The product is shipped at a|Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70°C as supplied. 1 month, 2 to 8°C under sterile conditions after reconstitution. 3 months, -20 to -70°C under sterile conditions after reconstitution. |Other IL-2 Proteins: Reco|IL-2 Polyclonal Antibody IL-2 Polyclonal Antibody IL-2 Monoclonal Antibody IL-2 Monoclonal Antibody IL-2 Monoclonal Antibody