IL-31 Protein

Description:
|Introduction IL-31 produced by activated Th2-type T cells, cooperates with a heterodimeric receptor consisting of IL-31 Receptor Anatagonist and Onconstatin-M Receptor that is continuesly expressed on epithelial cells and keratinocytes. IL-31 plays a role in the promotion of allergic skin disorders and in regulating other allergic diseases, such as asthma. IL-31 is involved in the itching sensation and endorses the scratching behavior in NC/Nga mice with atopic dermatitis. IL-31 expression is connectd with CLA(+) T cells and contributes to the development of atopic dermatitis-induced skin inflammation and pruritus. IL-31 is a powerful inducer of proinflammatory mediators in human colonic SEMFs. IL-31 takes |E. coli-derived. A single, non-glycosylated, polypeptide chain containing 141 amino acids and having a molecular mass of 15.7 kDa. Purity: > 97% by SDS-|The IL31 (1 ug/ml) was lyophilized from 10 mM sodium Phosphate pH-7.4. Reconstitution: It is recommended to reconstitute the lyophilized IL31 in sterile 18 M?-cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions. Shipping: The product is shipped at a|Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70°C as supplied. 1 month, 2 to 8°C under sterile conditions after reconstitution. 3 months, -20 to -70°C under sterile conditions after reconstitution. |Other IL-31 Proteins: Recombinant Human IL-31 Protein Recombinant Human IL-31 Protein