IL-33 Protein

Description:
|Introduction Interleukin-33 (IL-33) is a 32 kDa proinflammatory cytokine that may also regulate gene transcription in producer cells. IL-33 is structurally related to IL-1, which induces helper T cells to produce type 2 cytokines and acts through the receptor IL1RL-1 (IL1 receptor-like-1), which is known also as ST2. Binding of IL-33 to this receptor activates NF-kap|E. coli-derived. N-terminal sequence analysis: 17.5 kDa. The ED50 as determined by the dose-dependent stimulation of the proliferation of murine D10S cells is Purity: > 97% by SDS-|Lyophilized from a concentrated (1 mg/ml) solution containing 20 mM Phosphate buffer pH-7.4, 150 mM sodium chloride, 1 mM EDTA and 2 mM b-ME. Reconstitution: It is recommended to reconstitute the lyophilized IL-33 in sterile 18 M?-cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions. Shipping: The product is shipped with ice |Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70°C as supplied. 1 month, 2 to 8°C under sterile conditions after reconstitution. 3 months, -20 to -70°C under sterile conditions after reconstitution.