IL-4 Protein

Description:
|Introduction The interleukin 4 receptor binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal of this cytokine. This gene, IL3, IL5, IL13, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene |E. coli-derived. N-terminal sequence analysis: Met-His-Lys-Cys-Asp. The ED50 as determined by the dose-dependent stimulation of TF-1 cells is less than 2 ng/ml, corresponding to a Specific Activity of 5.0 x 106 IU/mg. Purity: > 95% by SEC-HPLC and reducing SDS-|Lyophilized from a 0.2 um filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4. Reconstitution: Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in 1X PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. Shipping: The product is shipped with ice |Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70°C as supplied. 1 month, 2 to 8°C under sterile conditions after reconstitution. 3 months, -20 to -70°C under sterile conditions after reconstitution.