IL-15 Protein

Description:
|Introduction Human interleukin 15 (IL-15) is a cytokine that regulates T cell and natural killer cell activation and proliferation. IL15 binds to the alpha subunit of the IL15 receptor (IL15RA) with high affinity. IL15 also binds to the beta and gamma chains of the IL2 receptor, but not the alpha subunit of the IL2 receptor. IL15 is structurely and functionally related to IL2. Both cytokines share some subunits of receptors, allowing them to compete for and negatively regulate each other’s activity. CD8+ memory T cell nu|E. coli-derived. A single, non-glycosylated polypeptide chain containing 114 amino acids and having a molecular mass of 13,118 Dalton. The ED50 as determined by the dose-dependant stimulation of the proliferation of mouse CTLL-2 was found to be Purity: > 95% by SDS-|Lyophilized from a concentrated (1 ug/ml) solution containing no additives. Reconstitution: It is recommended to reconstitute the lyophilized Interleukin-15 in sterile 18 M?-cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions. Shipping: The product is shipped at a|Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70°C as supplied. 1 month, 2 to 8°C under sterile conditions after reconstitution. 3 months, -20 to -70°C under sterile conditions after reconstitution.