IL-20 Protein

Description:
|Introduction IL20 is a cytokine structurally related to interleukin 10 (IL10). IL20 cytokine has been shown to transduce its signal through signal transducer and activator of transcription 3 (STAT3) in keratinocytes. A specific receptor for this cytokine is found to be expressed in skin and upregulated dramatically in psoriatic skin, suggesting a role for this protein in epidermal function and psoriasis. |Reco|E. coli-derived. A single, non-glycosylated polypeptide chain containing 152 amino acids and having a total molecular mass of 17,584 Dalton. N-terminal sequence analysis: Met-Leu-Lys-Thr-Leu. The biological activity was determined by measuring the dose dependent activation of STAT3 in human epidermal keratinocytes (HEK2a cells). Significant STAT3 activation is observed with >100 ug/ml corresponding to a specific activity of 1,000 U/mg of Interleukin-20 reco|> 95% by SDS-|Lyophilized from a concentrated (1 ug/ml) solution containing no additives. Reconstitution: It is recommended to reconstitute the lyophilized Interleukin-20 in sterile 18 M?-cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions. Shipping: The product is shipped at a|Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70°C as supplied. 1 month, 2 to 8°C under sterile conditions after reconstitution. 3 months, -20 to -70°C under sterile conditions after reconstitution. |Other IL-20 Proteins: Reco|IL-20 Polyclonal Antibody