Animal-Free Recombinant Human FGF-4
FGF-4 is a heparin binding growth factor that is a member of the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-4 signals through the FGFR 1c, 2c, 3c, and 4. Recombinant human FGF-4 is a 19.7 kDa protein consisting of 182 amino acid residues. Manufactured using all non-animal reagents.
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Source: |
E. Coli
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Purity:
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Above 95% as determined by SDS-PAGE Analysis.
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Cross Reactivity: |
Mouse, Rat
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Biological Activity
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The ED50 as determined by the dose-dependent stimulation of thymidine uptake by BaF3 cells expressing FGF-receptors is ≤ 0.5 ng/ml, corresponding to a specific activity of ≥ 2 x 106 units/mg.
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AA Sequence
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GRGGAAAPT APNGTLEAE LERRWESLV ALSLARLPV AAQPKEAAV QSGAGDYLL GIKRLRRLY CNVGIGFHL QALPDGRIG GAHADTRDS LLELSPVER GVVSIFGVA SRFFVAMSS KGKLYGSPF FTDECTFKE ILLPNNYNA YESYKYPGM FIALSKNGK TKKGNRVSP TMKVTHFLP RL
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| Research Interest: | , , Proliferation and Cell Cycle |
| Cell Type: | |
| Protein Cross Reactivity: | Mouse, Rat |