Animal-Free Recombinant Human FGF-acidic
FGF-acidic is one of 23 known members of the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-acidic is a non-glycosylated heparin binding growth factor that is expressed in the brain, kidney, retina, smooth muscle cells, bone matrix, osteoblasts, astrocytes and endothelial cells. FGF-acidic has the ability to signal through all the FGF receptors. Recombinant human FGF-acidic is a 16.0 kDa protein consisting of 141 amino acid residues. Manufactured using all non-animal reagents.
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Source: |
E. Coli
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Purity:
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Above 95% as determined by SDS-PAGE Analysis.
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Cross Reactivity: |
Cow, Mouse, Pig, Rat, Shark, Squid
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Biological Activity
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Assay #1: The ED50 as determined by the dose-dependent stimulation of thymidine uptake by BaF3 cells expressing FGF receptors is ≤ 10 ng/ml, corresponding to a specific activity of ≥ 1 x 105 un
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AA Sequence
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MFNLPPGNY KKPKLLYCS NGGHFLRIL PDGTVDGTR DRSDQHIQL QLSAESVGE VYIKSTETG QYLAMDTDG LLYGSQTPN EECLFLERL EENHYNTYI SKKHAEKNW FVGLKKNGS CKRGPRTHY GQKAILFLP LPVSSD
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| Research Interest: | , , , , , Proliferation and Cell Cycle |
| Cell Type: | , Endothelial Cells |
| Protein Cross Reactivity: | Cow, Mouse, Pig, Rat, Shark, Squid |