Animal-Free Recombinant Murine G-CSF
G-CSF is a hematopoietic growth factor that stimulates the development of committed progenitor cells to neutrophils and enhances the functional activities of the mature end-cell. It is produced in response to specific stimulation by a variety of cells including macrophages, fibroblasts, endothelial cells and bone marrow stroma. G-CSF is being used clinically to facilitate hematopoietic recovery after bone marrow transplantation. Human and murine G-CSF are cross-species reactive. Recombinant murine G-CSF is a 19.0 kDa protein consisting of 179 amino acid residues. Manufactured using all non-animal reagents.
|
Source: |
E. Coli
|
|   | |
|
Purity:
|
Above 98% as determined by SDS-PAGE Analysis.
|
|   | |
|
Cross Reactivity: |
NULL
|
|   | |
|
Biological Activity
|
The ED50 was determined by the dose-dependent stimulation of the proliferation of murine NFS-60 cells is ≤ 0.05 ng/ml, corresponding to a s
|
|   | |
|
AA Sequence
|
MVPLVTVSA LPPSLPLPR SFLLKSLEQ VRKIQASGS VLLEQLCAT YKLCHPEEL VLLGHSLGI PKASLSGCS SQALQQTQC LSQLHSGLC LYQGLLQAL SGISPALAP TLDLLQLDV ANFATTIWQ QMENLGVAP TVQPTQSAM PAFTSAFQR RAGGVLAIS YLQGFLETA RLALHHLA
|
| Research Interest: | , , , , Inflammation, |
| Cell Type: | , , Endothelial Cells |
| Protein Cross Reactivity: | NULL |