Anti-Mouse CD71 (Transferrin Receptor) APC
The R17217 antibody specifically reacts with mouse CD71, a type II homodimeric transmembrane protein. CD71 mediates the uptake of transferrin-iron complexes and is highly expressed on the surface of cells of the erythroid lineage. It is known as the transferrin receptor or T9. The expression of CD71 on resting mature lymphocytes is low. PSI-699
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Clone
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R17217
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Format: |
APC
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Applications
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FC
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Reactivity
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Mouse
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Isotype:
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Mouse IgG2a, kappa
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Preperation:
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The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze. The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
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Formulation:
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Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
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References:
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Ulbrich, Karsten, et al. “Transferrin-and transferrin-receptor-antibody-modified nanoparticles enable drug delivery across the blood–brain barrier (BBB).”European Journal of Pharmaceutics and Biopharmaceutics 71.2 (2009): 251-256. Lesley, J., Hyman, R., Schulte, R., & Trotter, J. (1984). Expression of transferrin receptor on murine hematopoietic progenitors. Cellular immunology,83(1), 14-25. van Rooy, I., Mastrobattista, E., Storm, G., Hennink, W. E., & Schiffelers, R. M. (2011). Comparison of five different targeting ligands to enhance accumulation of liposomes into the brain. Journal of Controlled Release, 150(1), 30-36. |