Recombinant Human Eotaxin-3 (CCL26)
Eotaxin-3 is a CC chemokine that signals through the CCR3 receptor. It is produced by endothelial cells stimulated with IL-4 or IL-13. Eotaxin-3 selectively targets cells expressing CCR3, including eosinophils, basophils, T cells and monocytes. Eotaxin-3 has similar activity to Eotaxin and Eotaxin-2, but the three Eotaxins share only a low degree of sequence homology. Recombinant human Eotaxin-3 is an 8.4 kDa protein containing 71 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines. VcMMAE
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Source: |
E. Coli
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Purity:
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Above 98% as determined by SDS-PAGE Analysis.
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Cross Reactivity: |
Mouse
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Biological Activity
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Determined by its ability to chemoattract human CCR3/HEK 293 cells. The maximum activity was achieved at 2ug/ml.
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AA Sequence
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TRGSDISKT CCFQYSHKP LPWTWVRSY EFTSNSCSQ RAVIFTTKR GKKVCTHPR KKWVQKYIS LLKTPKQL
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| Research Interest: | , Proliferation and Cell Cycle, |
| Cell Type: | , , Endothelial Cells |
| Protein Cross Reactivity: | Mouse |