Recombinant Human MIP-3 (CCL23)
MIP-3 is a CC chemokine that signals through the CCR1 receptor. MIP-3 chemoattracts monocytes, resting T-lymphocytes and neutrophils, but does not chemoattract activated lymphocytes. Additionally, MIP-3 has been shown to inhibit colony formation of bone marrow myeloid immature progenitors. Recombinant human MIP-3 is an 11.3 kDa protein containing 99 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines. Pacritinib
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Source: |
E. Coli
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Purity:
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Above 98% as determined by SDS-PAGE Analysis.
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Cross Reactivity: |
NULL
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Biological Activity
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Determined by its ability to chemoattract human T cell population using a concentration of 10-50 ng/ml.
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AA Sequence
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RVTKDAETE FMMSKLPLE NPVLLDRFH ATSADCCIS YTPRSIPCS LLESYFETN SECSKPGVI FLTKKGRRF CANPSDKQV QVCMRMLKL DTRIKTRKN
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| Protein Cross Reactivity: | NULL |