Recombinant Murine JE/MCP-1 (CCL2)
The MCP proteins belong to the CC chemokine family, and signal through CCR2 and, with the exception of MCP-1, other CCR receptors. The MCP proteins chemoattract and activate monocytes, activated T cells, basophils, NK cells, and immature dendritic cells. The MCP family cross reacts across species. Recombinant murine JE is a 13.8 kDa protein containing 125 amino acid residues including the four highly conserved cysteine residues present in the CC chemokines. Asunaprevir
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Source: |
E. Coli
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Purity:
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Above 98% as determined by SDS-PAGE Analysis.
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Cross Reactivity: |
Bacteria, Human
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Biological Activity
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Determined by its ability to chemoattract Balb/C mouse spleen MNCs using a concentration range of 1.0-20.0 ng/ml.
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AA Sequence
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QPDAVNAPL TCCYSFTSK MIPMSRLES YKRITSSRC PKEAVVFVT KLKREVCAD PKKEWVQTY IKNLDRNQM RSEPTTLFK TASALRSSA PLNVKLTRK SEANASTTF STTTSSTSV GVTSVTVN
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| Research Interest: | , , , , Inflammation, |
| Cell Type: | , , |
| Protein Cross Reactivity: | Bacteria, Human |