Nan Province, China Complete list of author information and facts is accessible at the finish of the articleThe Author(s). 2017 Open Access This short article is distributed below the terms of the Inventive Commons Attribution four.0 International License (http:creativecommons.orglicensesby4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided you give proper credit to the original author(s) along with the supply, supply a hyperlink to the Inventive Commons license, and indicate if modifications were created. The Creative Commons Public Domain Dedication waiver (http:creativecommons.orgpublicdomainzero1.0) applies towards the data produced offered within this article, unless otherwise stated.Chu et al. Trials (2017) 18:Web page 2 ofBackground Placenta accreta (PA), a type of morbidly adherent placenta, includes an absence of decidua basalis; the placenta normally adheres towards the underlying myometrium [1]. This morbidly obstetric condition is a serious complication for the duration of delivery. It can be closely linked with huge hemorrhage, which could endanger the lives of both mother and infant [2, 3]. In individuals with PA, median intraoperative blood loss is about 2000 ml throughout delivery, and in 10 of your situations it has been more than ten,000 ml in some institutions [4, 5]. Various pathophysiological situations are involved in massive hemorrhage from patients with PA throughout cesarean section, including pelvic viscera injury for the bladder, ureter, bowel, or other organs through the surgery. When enormous hemorrhage can’t be successfully controlled, multisystem organ failure (MOF) and disseminated intravascular coagulation (DIC) will follow [6]. For that reason, placenta accreta poses a serious threat to the security in the mother. However, in recent years, the incidence of PA has risen together with the rising rate of cesarean deliveries [7]. In accordance with a Planet Well being Organization (WHO) report, China has develop into the country together with the highest rate of cesarean sections, as much as 68 . China will face a big challenge with its two-child family members policy initiation. In America, the cesarean delivery rate is going to be 56.2 in the event the cesarean rate continues to develop since it has previously, and there are going to be 6236 patients with placenta previa, 4504 individuals with placenta accreta, and 130 maternal deaths annually [8]. For that reason, research evaluating the effects of distinctive perioperative management approaches based on various modalities inside the remedy of placenta accreta are required. Within the regular method, hysterectomy following cesarean section is normally indicated as the therapy alternative in individuals with morbidly adherent placenta. This therapy reduces maternal morbidity, but it outcomes in infertility [9]. To reduce intraoperative hemorrhage and facilitate surgery, some novel remedy choices have been described, which includes proximal ligation in the internal iliac STF62247 artery or uterine artery and vascular balloon catheters placed within the iliac artery, uterine artery, or even the abdominal aorta [10]. Amongst the many remedy measures, prophylactic balloon occlusion of your abdominal aorta appears to be additional advantageous than other individuals [11, 12]. Recently, a large-sample retrospective study from our single center also shows that prophylactic abdominal aortic PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/2129546 balloon occlusion (AABO) features a promising future [13, 14]. These retrospective research strongly suggest that we want an adequately powered prospective study to demonstrate the advantages and dangers. As a result, the primary aim with the study is to investigate the advantage.