Name : IP-10/CXCL10, Mouse

Product Concentration :

Background :
TAFA-2 also named FAM19A2 belongs to the TAFA family of chemokine­like proteins. Like other members of the FAM19/TAFA family, with the exception of TAFA5, mature TAFA1 to 4 contain 10 regularly spaced cysteine residues. Human TAFA2 is 97% aa identical to mouse TAFA2. TAFA2 expression can be detected in the central nervous system (CNS), colon, heart, lung, spleen, kidney, and thymus, but its expression in the CNS is 50­ to 1000­fold higher than in other tissues. Within the CNS, TAFA2 expression is highest in the occipital and frontal cortex (3­ to 10­fold more abundantly expressed than in other cortical regions) and medulla. The biological functions of TAFA family members remain to be determined, but there are a few tentative hypotheses.

Biological Activity :
Fully biologically active when compared to standard. The biologically active determined by a chemotaxis bioassay using human peripheral blood lymphocytes is in a concentration range of 0.1-10.0 ng/ml in the presence of IL-2.

expression system :
E. coli

Tag :
CXCL10 (Ile22-Pro98)Accession # Q548V9

Protein Accession No. :
Q548V9

Synonyms :
Small inducible cytokine B10; CXCL10; 10 kDa interferon-gamma-induced protein; Gamma-IP10; IP-10; chemokine (C-X-C motif) ligand 10; C7; IFI10; INP10; crg-2; mob-1; SCYB10; gIP-10

Molecular Weight :

Purity :
> 97% as analyzed by SDS-PAGE> 97% as analyzed by HPLC

Product Concentration :
Lyophilized from a 0.2 μm filtered solution in 2 × PBS, pH 7.4.

Storage and Stability :
Upon receiving, this product remains stable for up to 6 months at -70°C or -20°C. Upon reconstitution, the product should be stable for up to 1 week at 4°C or up to 3 months at -20°C. Avoid repeated freeze-thaw cycles.

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