Name : April, Mouse
Product Concentration :
Background :
A Proliferation-inducing Ligand (April)) also known as TNSF13A, Tall-2, and TRDL-1, is a member of the TNF ligand (TNFL) superfamily. April is most similar to B-cell activation factor (BAFF) with which it shares 30% sequence identity, compete for two receptors, TACI and BCMA. APRIL is expressed at low levels in lymphoid tissue and is over-expressed by a number of tumors. April has a proliferative effect on both normal and tumor cell lines in vitro and in vivo. APRIL seems to be involved in the regulation of death and proliferation of tumor cells, but there are still contradictory findings regarding its overall biological effects.
Biological Activity :
Measured by its ability to induce cell proliferation of RPMI 8226 Cells.
expression system :
E. coli
Tag :
Expressed with an N-terminal Met. April (Arg50-Leu241)Accession # Q9D777
Protein Accession No. :
Q9D777
Synonyms :
A proliferating-inducing ligand; TNFSF13; TRDL-1 alpha
Molecular Weight :
~21.9 kDa, on SDS-PAGE under reducing conditions.
Purity :
> 95% as analyzed by SDS-PAGE> 95% as analyzed by HPLC
Product Concentration :
Lyophilized after extensive dialysis against 20 mM acetic acid.
Storage and Stability :
Upon receiving, this product remains stable for up to 6 months at lower than -70°C. Upon reconstitution, the product should be stable for up to 1 week at 4°C or up to 3 months at -20°C. For long term storage it is recommended that a carrier protein (example 0.1% BSA) be added. Avoid repeated freeze-thaw cycles.
Related category websites: https://www.medchemexpress.com/recombinant-proteins.html
Popular product recommendations:
CD38 Protein
SCGB3A2 Protein
Popular categories:
Butyrophilin Like 3 (BTNL3)
Adhesion G Protein-Coupled Receptor G5 (GPR114)