Name : S100A1, His, Human

Product Concentration :

Background :
S100 calcium-binding protein A1 (S100A1) is a small calcium binding protein with EF-hand structures and belongs to the S100 family. S100 proteins include at least 25 members which are located as a cluster on human chromosome 1q21. S100A1 is found in the heart, skeletal muscle, brain, and kidney.S100A1 mainly resides on the sarcoplasmic reticulum, mitochondria and myofilaments. S100A1 may function in stimulation of Ca2+ induced Ca2+ release, inhibition of microtubule assembly, and inhibition of protein kinase C-mediated phosphorylation. Reduced expression of this protein has been implicated in cardiomyopathies.

Biological Activity :

expression system :
E. coli

Tag :
Poly-His S100A1 (Met1-Ser94)Accession # P23297 N-term C-term

Protein Accession No. :
P23297

Synonyms :
Protein S100-A1; S100 calcium-binding protein A1; S-100 protein alpha subunit; S-100 protein alpha chain; S100A1; S100A; S100; S100-alpha; S100-A1

Molecular Weight :
~11.5 kDa, on SDS-PAGE under reducing conditions.

Purity :
> 95% as analyzed by SDS-PAGE> 95% as analyzed by HPLC

Product Concentration :
Lyophilized after extensive dialysis against 20 mM Tris-HCl, 0.1 mM EDTA, pH 7.0.

Storage and Stability :
Upon receiving, this product remains stable for up to 6 months at lower than -70°C. Upon reconstitution, the product should be stable for up to 1 week at 4°C or up to 3 months at -20°C. For long term storage it is recommended that a carrier protein (example 0.1% BSA) be added. Avoid repeated freeze-thaw cycles.

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