Name : GH, Mouse
Product Concentration :
Background :
Growth Hormone (GH), is a member of the somatotropin / prolactin family of hormones which play an important role in growth control. The gene, along with four other related genes, is located at the growth hormone locus on chromosome 17 where they are interspersed in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. The five genes share a remarkably high degree of sequence identity. Alternative splicing generates additional isoforms of each of the five growth hormones, leading to further diversity and potential for specialization. This particular family member is expressed in the pituitary but not in placental tissue as is the case for the other four genes in the growth hormone locus. Mutations in or deletions of the gene lead to growth hormone deficiency and short stature.
Biological Activity :
Recombinant mouse growth hormone is fully biologically active when compared to standard human growth hormone which is 3.0 units/mg.
expression system :
E. coli
Tag :
GH (Phe27-Phe216)Accession # P06880
Protein Accession No. :
P06880
Synonyms :
GH1; GH; GHN; GH-N; hGH-N; Pituitary growth hormone; Growth hormone 1; Somatotropin
Molecular Weight :
Purity :
> 95% as analyzed by SDS-PAGE> 95% as analyzed by SEC-HPLC
Product Concentration :
Lyophilized after extensive dialysis against 50 mM Tris-HCl, pH 8.0, 500 mM NaCl buffer.
Storage and Stability :
Upon receiving, this product remains stable for up to 6 months at -70°C or -20°C. Upon reconstitution, the product should be stable for up to 1 week at 4°C or up to 3 months at -20°C. Avoid repeated freeze-thaw cycles.
Related category websites: https://www.medchemexpress.com/recombinant-proteins.html
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