Name : Histone H3, His, Human

Product Concentration :

Background :
Histone H3 is one of the five main histones involved in the structure of chromatin in eukaryotic cells. Featuring a main globular domain and a long N-terminal tail, H3 is involved with the structure of the nucleosomes of the “beads on a string” structure. Histone proteins are highly post-translationally modified however Histone H3 is the most extensively modified of the five histones. Histone H3 is an important protein in the emerging field of epigenetics, where its sequence variants and variable modification states are thought to play a role in the dynamic and long term regulation of genes.

Biological Activity :

expression system :
E. coli

Tag :
Expressed with additional DDDDK amino acids at the N-terminal. Poly-His Histone H3 (Met1-Ala136)Accession # P68431 N-term C-term

Protein Accession No. :

Synonyms :
Histone H3

Molecular Weight :

Purity :
> 90% as analyzed by SDS-PAGE and Commassie blue staining

Product Concentration :
Lyophilized from PBS, pH 7.4.

Storage and Stability :
Upon receiving, this product remains stable for up to 24 months at -70°C or -20°C. Once rehydrated, aliquot and store at -20°C.

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