Name : FGF-21, Mouse
Product Concentration :
Background :
Fibroblast growth factor-21 (FGF21) belongs to the large FGF family which has at least 23 members. Along with FGF-19/15 and FGF-23, FGF-21 is categorized as a member of the atypical FGF subfamily, as it must be complexed to the Klotho co-receptor in order to bind to the FGF receptors and activate the downstream signaling pathway. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion.
Biological Activity :
ED50 2.0 × 103 units/mg.
expression system :
E. coli
Tag :
FGF-21 (Ala29-Ser210)Accession # Q9JJN1
Protein Accession No. :
Q9JJN1
Synonyms :
FGF21; fibroblast growth factor-21; FGFL
Molecular Weight :
~19.9 kDa, on SDS-PAGE under reducing conditions.
Purity :
> 97% as analyzed by SDS-PAGE> 97% as analyzed by HPLC
Product Concentration :
Lyophilized after extensive dialysis against PBS.
Storage and Stability :
Upon receiving, this product remains stable for up to 6 months at lower than -70°C. Upon reconstitution, the product should be stable for up to 1 week at 4°C or up to 3 months at -20°C. For long term storage it is recommended that a carrier protein (example 0.1% BSA) be added. Avoid repeated freeze-thaw cycles.
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