Name : MIP-2/CXCL2, Mouse

Product Concentration :

Background :
Chemokine (C-X-C motif) ligand 2 (CXCL2) is a small cytokine belonging to the CXC chemokine family that is also referred to as macrophage inflammatory protein 2-alpha (MIP2-alpha), Growth-regulated protein beta (Gro-beta) and Gro oncogene-2 (Gro-2). CXCL2 is secreted by monocytes and macrophages and is chemotactic for polymorphonuclear leukocytes and hematopoietic stem cells. CXCL2’s amino acid sequence is 90% identical to the amino acid sequence of related chemokine, CXCL1. CXCL2 signals through the CXCR2 receptor.

Biological Activity :
The EC50 value of Mouse MIP-2/CXCL2 on Ca2+ mobilization assay in CHO-K1/mCXCR2 (mouse CXCR2 stably expressed in CHO-K1 cells) is less than 200.0 ng/ml.

expression system :
HEK 293

Tag :
MIP-2 (Ala28-Asn100)Accession # P10889

Protein Accession No. :
P10889

Synonyms :
CINC-3; GRO beta; MGSA-beta; MIP-2

Molecular Weight :
~7.8 kDa, on SDS-PAGE under reducing conditions.

Purity :
> 95% as analyzed by SDS-PAGE

Product Concentration :
Lyophilized from a 0.2 μm filtered solution in PBS.

Storage and Stability :
Upon receiving, this product remains stable for up to 6 months at lower than -70°C. Upon reconstitution, the product should be stable for up to 1 week at 4°C or up to 3 months at -20°C. For long term storage it is recommended that a carrier protein (example 0.1% BSA) be added. Avoid repeated freeze-thaw cycles.

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