Name : BAFF-R, Human

Product Concentration :

Background :
BAFF Receptor (BAFF-R), a member of the TNFR superfamily, is highly expressed in spleen, lymph node, and resting B cells and to some extent in activated B cells, resting CD4+ cells and peripheral blood leukocytes. BAFF-R is a type III transmembrane protein that binds with high specificity to BAFF (TNFSF13B). BAFF-R/BAFF signaling plays a critical role in B cell survival and maturation.

Biological Activity :
Fully biologically active when compared to standard. The ED50 as determined by its ability to block BAFF induced mouse splenocyte survival is 1.0-5.0 μg/ml in the presence of 1.0 μg/ml of rHuBAFF.

expression system :
E. coli

Tag :
BAFF-R (Met1-Gly76)Accession # Q96RJ3

Protein Accession No. :

Synonyms :
BAFF Receptor; BLyS receptor 3; CD_antigen: CD268;

Molecular Weight :

Purity :
> 95% as analyzed by SDS-PAGE

Product Concentration :
Lyophilized from a 0.2 μm filtered solution in 20 mM PB, pH 8.0, 500 mM NaCl.

Storage and Stability :
Upon receiving, this product remains stable for up to 6 months at -70°C or -20°C. Upon reconstitution, the product should be stable for up to 1 week at 4°C or up to 3 months at -20°C. Avoid repeated freeze-thaw cycles.

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