Name : RANTES/CCL5, Human

Product Concentration :

Background :
CCL5 or RANTES (acronym for Regulated upon Activation, Normal T cell Expressed and presumably Secreted), was initially discovered by subtractive hybridization as a transcript expressed in T cells but not B cells. Eosinophilchemotactic activities released by thrombinstimulated human platelets have also been purified and found to be identical to RANTES. Besides T cells and platelets, RANTES has been reported to be produced by renal tubular epithelium, synovial fibroblasts and selected tumor cells.

Biological Activity :
Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human peripheral blood monocytes is in a concentration range of 1.0-10.0 ng/ml.

expression system :
E. coli

Tag :
CCL5 (Ser24-Ser91)Accession # P13501

Protein Accession No. :

Synonyms :
CCL-5; D17S136E; RANTES; SCYA5; SIS-delta; SISd; TCP228; eoCP; C-C motif chemokine ligand 5

Molecular Weight :

Purity :
> 98% as analyzed by SDS-PAGE> 98% as analyzed by HPLC

Product Concentration :
Lyophilized from a 0.2 μm filtered solution in 20 mM PB, pH 7.4, 100 mM NaCl.

Storage and Stability :
Upon receiving, this product remains stable for up to 6 months at -70°C or -20°C. Upon reconstitution, the product should be stable for up to 1 week at 4°C or up to 3 months at -20°C. Avoid repeated freeze-thaw cycles.

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