Nan Province, China Full list of author facts is offered at the end of your articleThe Author(s). 2017 Open Access This short article is distributed under the terms in the Creative Commons Attribution four.0 International License (http:creativecommons.orglicensesby4.0), which permits unrestricted use, distribution, and reproduction in any medium, offered you give acceptable credit for the original author(s) plus the supply, present a hyperlink to the Inventive Commons license, and indicate if adjustments have been created. The Inventive Commons Public Domain Dedication waiver (http:creativecommons.orgpublicdomainzero1.0) applies for the data created accessible in this short article, unless otherwise stated.Chu et al. Trials (2017) 18:Web page 2 ofBackground Placenta accreta (PA), a sort of morbidly adherent placenta, requires an absence of decidua basalis; the placenta always adheres to the underlying myometrium [1]. This morbidly obstetric situation is usually a serious complication for the duration of delivery. It is closely linked with massive hemorrhage, which could endanger the lives of each mother and baby [2, 3]. In individuals with PA, median intraoperative blood loss is about 2000 ml during delivery, and in ten of your cases it has been greater than ten,000 ml in some institutions [4, 5]. Many pathophysiological conditions are involved in massive hemorrhage from individuals with PA during cesarean section, such as pelvic viscera injury towards the bladder, ureter, bowel, or other organs throughout the surgery. When huge hemorrhage can’t be correctly controlled, multisystem organ failure (MOF) and disseminated intravascular coagulation (DIC) will adhere to [6]. As a result, placenta accreta poses a significant threat to the security from the mother. Even so, in recent years, the incidence of PA has risen using the escalating price of cesarean deliveries [7]. In line with a World Health Organization (WHO) report, China has become the country with the highest price of cesarean sections, as much as 68 . China will face a significant challenge with its two-child family members policy initiation. In America, the cesarean delivery rate might be 56.2 if the cesarean rate continues to develop because it has in the past, and there is going to be 6236 patients with placenta previa, 4504 patients with placenta accreta, and 130 maternal deaths annually [8]. Therefore, studies evaluating the effects of various perioperative management approaches based on various modalities within the treatment of placenta accreta are essential. Inside the classic technique, hysterectomy following cesarean section is generally indicated because the treatment selection in patients with morbidly adherent placenta. This remedy reduces maternal morbidity, nevertheless it outcomes in infertility [9]. To minimize intraoperative hemorrhage and facilitate surgery, some novel treatment options happen to be described, such as proximal ligation with the internal iliac artery or uterine artery and vascular balloon catheters placed in the iliac artery, uterine artery, or perhaps the abdominal aorta [10]. Amongst the a lot of remedy measures, prophylactic balloon occlusion of your abdominal aorta seems to become additional advantageous than other folks [11, 12]. Recently, a large-sample retrospective study from our single center also shows that prophylactic abdominal aortic PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/2129546 balloon occlusion (AABO) includes a promising Angiotensin II 5-valine chemical information future [13, 14]. These retrospective research strongly recommend that we require an adequately powered potential study to demonstrate the added benefits and dangers. Hence, the main aim in the study is always to investigate the benefit.