Name : FGF-18, Human
Product Concentration :
Background :
Fibroblast Growth Factor-18 (FGF-18) is a heparin-binding growth factor that is a member of the FGF family. FGF-18 signals through FGFR 1c, 2c, 3c, and 4. FGF-18 plays an important role in the regulation of cell proliferation, cell differentiation and cell migration. FGF-18 is required for normal ossification and bone development. It can also stimulate hepatic and intestinal proliferation.
Biological Activity :
ED50 1.0 × 105 units/mg.
expression system :
E. coli
Tag :
Expressed with an N-terminal Met. FGF-18 (Ala27-Arg199)Accession # O76093
Protein Accession No. :
O76093
Synonyms :
FGF18; Fibroblast Growth Factor-18; zFGF5; FGFI
Molecular Weight :
~20.3 kDa, on SDS-PAGE under reducing conditions.
Purity :
> 95% as analyzed by SDS-PAGE> 95% as analyzed by HPLC
Product Concentration :
Lyophilized after extensive dialysis against PBS.
Storage and Stability :
Upon receiving, this product remains stable for up to 6 months at lower than -70°C. Upon reconstitution, the product should be stable for up to 1 week at 4°C or up to 3 months at -20°C. For long term storage it is recommended that a carrier protein (example 0.1% BSA) be added. Avoid repeated freeze-thaw cycles.
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